Thrombolysis in acute ischemic stroke: Experience from a tertiary care centre in India

Authors: Vikram Huded, Romnesh De Souza, Rajesh Karalumangala Nagarajaiah, Syed Moeed Zafer, Rithesh Nair, Hariram Acharya
Publication date: 2014-1
Journal: Journal of neurosciences in rural practice
Volume: 5
Issue: 1
Pages: 25
Publisher: Medknow Publications
Description: Abstract The management of acute ischemic stroke has undergone a sea of change with the introduction of intravenous thrombolysis (IVT). Current guidelines state that the window period for IVT using rTPA is 4.5 hours. The MERCI, Multi Merci, and Penumbra trials in which patients with acute ischemic stroke were treated using endovascular treatment demonstrated better recanalisation in patients having a large vessel occlusion. However, recently published data from the three large trials IMS 3, Synthesis Expansion, and MR rescue, which compared endovascular treatment with intravenous therapy, failed to demonstrate superiority of endovascular treatment over IVT. In these trials, stent retrievers were used in very few patients. We present our results from a tertiary care center in India where patients are treated using intravenous as well as endovascular modalities. Among …
Total citations: Cited by 4
Scholar articles: Thrombolysis in acute ischemic stroke: Experience from a tertiary care centre in India | V Huded, R De Souza, RK Nagarajaiah, SM Zafer… – Journal of neurosciences in rural practice, 2014